Bleeding calf syndrome

Bovine neonatal pancytopenia (Bleeding calf syndrome) or Idiopathic haemorrhagic diathesis of calves (blood sweating disease)

The Veterinary Laboratory Agency and Scottish Agricultural Colleges have recently

diagnosed a disease in young calves (less than 3 weeks old), that results in unexplained bleeding or haemorrhaging from the skin, nares, mouth, rectum and injection sites and ear tags and with a raised temperature in some cases. It has been reported throughout England and Scotland in both dairy and beef herds and there have also been reports of similar cases from mainland Europe (Belgium, Germany, Netherlands).

It has been officially named 'Bovine neonatal pancytopenia' with the agreed common name of 'Bleeding Calf Syndrome'.

Symptoms

There have been different clinical manifestations seen, ranging from calves being found dead to unexpected excessive bleeding with secondary infection and malaise and on post mortem areas of bleeding or haemorrhage are seen throughout the carcase. The bone marrow also shows damage (aplasia) indicating that there is a problem with producing factors involved in blood clotting.

Most calves first showed clinical signs between 1-2 weeks of age and the majority died within a few days of first showing the clinical signs.

Numbers affected per herd vary considerably from the one calf to 3 to 5% of calves but generally numbers are very low and the indication is that this is unlikely to suddenly increase. Mortality would appear to be very high with few reports of calves recovering. The disease has been reported in both closed and open herds.

Causes

As yet the causal agent has not been elucidated but it is postulated that it may be an auto-immune mediated disease but poisoning, genetic abnormalities and drug reactions are all being considered. There are no known reports of any associated human illness and there appears to be absolutely no risk to human health and affected animals do not appear to be a human health risk.

The advice is to be vigilant and investigate any unexplained cases of bleeding or sudden death in young calves.

Further investigations are planned. Both the VLA and SAC are carrying out detailed investigations and a questionnaire has been developed to look for common features between cases.
الحقيقه صورتلكم هذه الحاله بعنايه لكن الصور بالنقال وماعندي الكابل اللي اربطه وانقله لذلك من ارجع للبيت انزله
حقيقه صور مخيفه
راح اشوفكم بعض الصور من النت

لقراءة المزيد يرجى الدخول هنا
http://www.defra.gov.uk/vla/diseases/docs/dis_bcs_oie.pdf
وساوايفيكم بالصور لحاله صادفتني قبل يومين
وملخص للبحوث الصادره حديثا على هيئة اسئله واجوبه للبساطه وللتوضيح
تحياتي

عاشت ايدك دكتور عيسى
والله مواضيع جدا مفيدة وقيمه
تحياتي الخالصه لك

شكرا لك اختي الاء
للمتابعه
اتمنى ان اكون قد قدمت شيئا جديدا
المرض حديث الانتشار في اوربا والرابط الذي تركته في ردي يوضح ذلك

Q1: What does the disease look like?
Clinical signs in calves include bleeding from apparently intact skin and also from injection and ear tagging sites together with signs of bleeding from visible mucous membranes, nose and rectum.


Q2: What causes the disease?
The symptoms are caused by an almost complete destruction of the bone marrow of the calf which produces the red and white blood cells vital for the animal’s immune system and blood clotting mechanisms.

This seems to be occurring at or around the time of birth, although it is uncertain whether the damage is occurring in the womb or soon after birth.

The cause is not yet known. There are a number of lines of investigation which are being pursued, which include management and environmental factors on the affected farms. Although there is currently no evidence of an infectious cause it cannot be totally ruled out at this point.

Q3: Does the disease lead to death?
Only a few calves have been affected in any one herd, but once affected they usually die. However there are reports, mainly anecdotal, of some affected calves making a full recovery. Only calves less than four weeks old are affected. The mothers of the affected calves are usually perfectly healthy.

Q4: How many case of this disease have occurred in Great Britain?
During 2009, 56 calves on 54 farms have been diagnosed with the condition in England, one calf on one farm have been diagnosed in Wales and 49 calves on 33 farms have been diagnosed in Scotland.

So far in 2010, 84 calves on 71 farms have been diagnosed with the condition in England, eight calves on seven farms have been diagnosed in Wales and 98 calves on 93 farms have been diagnosed in Scotland. These figures are up until the end of July.

The number of affected calves in each herd is very low. It is usually less than 1% and there is no sign of spread between animals.

Q5: Is it on the increase?
Recent media coverage suggests that there is an increase in the number of cases. At this moment it is not possible to confirm if there is an increase in the frequency of the condition.

Greater numbers are likely to reflect better awareness by farmers and private veterinary surgeons as a result of media interest and efforts by VLA and the Scottish Agricultural College (SAC) to comprehensively record and investigate the condition.

Q6: Does the disease occur in other countries?
Yes, cases have been reported in Germany, Belgium and Holland since 2008 although investigation suggests that the disease has been seen on some farms in Belgium since 2006. Cases have also been reported in France and Italy.

Q7: Is there any risk to humans through contact or food?
As the age of the animal affected is 0 – 4 weeks, they would not be entering the food chain. The age they are affected is very consistent and the disease has never been seen in older animals.

To date no infectious agent (known or novel) likely to have caused the condition has been identified in any of the tissues of affected calves.

There has been no direct evidence or reports of any potential transmission to people in Germany where the disease has been present for at least 18 months.

There is currently no evidence to suggest that the disease is infectious or contagious.

The Human Animal Infections and Risk Surveillance (HAIRS) group, which routinely meets to assess any risks to human health from emerging diseases, has been briefed and are considering the available data.

Q8: What is being done to find out more about the disease?
Research carried out by VLA and SAC, funded by Defra and the Scottish Government, is ongoing and is designed to identify the potential factors which might be causing the disease.

An international meeting took place in December 2009 in Marseille, France, to consider what is known about the condition and to identify the best way forward in collaborative investigation.

Q9: What should farmers do if they see the symptoms in their herd?
They should consult their own vet who can submit calves to their local VLA or SAC laboratory for a full examination

السلام عليكم
شكرا ابو نور للمشاركة المفيدة دائما انت منفرد بالمواضيع العلمية النادرة
تحياتي لك

شوهدت هذه الحاله التي صورتها في حقل لقح قطيعه بلقاح مضاد للانفلاونزا
يتردد كثيرا ان هذا اللقاح - من انتاج شركة بفايزر- يسبب ظهور هكذا حالات وانا شاهدت حالتين ليس بهذه الوضعيه انما فرط حساسيه حاد يسبب هلاك العجل بعد سويعات من التلقيح
ليس في كل الحقول تتكرر الحاله ولكني شاهدتها بالفعل
علما ان مضادات الهستامين غير مرخصه هنا في النمسا ولا في المانيا لاستخدام في الابقار
لوحظ كذلك ان خلط الليدوكائين بنسبة 5 مل مع السكر الكلوكوز بنسبة 200 مل وحقنها بالوريد تخفف شدة الاصابه علميا لايوجد تفسير منطقي لكن سريريا اثبتت جدواها في تاخير تدهور الحاله وليس علاجها لان نهايتها الموت الحتمي
تحياتيالك دكتور ابراهيم منورني والله